Master Modern Cardiology: Update in Clinical Cardiology 2025
About Lesson

Lesson Objectives:

  • Review key anatomical structures and their functions.

  • Understand the principles of myocardial perfusion and coronary circulation.

  • Discuss the role of the autonomic nervous system in cardiovascular function.

Key Concepts

🔹 Coronary Circulation:
The heart receives its blood supply from the left and right coronary arteries:

  • Left main coronary artery (LMCA) → bifurcates into the LAD (left anterior descending) and LCx (left circumflex).

  • Right coronary artery (RCA) → supplies the right atrium, right ventricle, SA node, and AV node.

🔹 Myocardial Perfusion:

  • Coronary blood flow occurs mainly during diastole (unlike systemic circulation, which is continuous).

  • Factors affecting perfusion include coronary artery stenosis, tachycardia, and endothelial dysfunction.

🔹 Electrophysiology & Conduction System:
The heart’s electrical conduction system includes:
1️⃣ Sinoatrial (SA) Node – the natural pacemaker (60-100 bpm).
2️⃣ Atrioventricular (AV) Node – delays conduction, allowing ventricular filling.
3️⃣ Bundle of His & Purkinje Fibers – ensure synchronized ventricular contraction.

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