Master Modern Cardiology: Update in Clinical Cardiology 2025
About Lesson

Lesson Objectives:

  • Compare PCI vs. CABG for coronary artery disease.

  • Review indications for valve replacement (TAVR vs. surgical).

  • Understand the role of mechanical circulatory support (LVAD, ECMO).

PCI vs. CABG – When to Choose?

Criteria PCI (Stents) CABG (Surgery)
Indications 1-2 vessel disease, STEMI/NSTEMI Left main disease, 3-vessel CAD, DM
Recovery Fast, <1 week Slower, ~6 weeks
Long-term outcomes Higher restenosis risk Better long-term survival

Valve Interventions: TAVR vs. Surgical AVR

✔️ TAVR (Transcatheter Aortic Valve Replacement)

  • Indicated for severe aortic stenosis (AS) in elderly/high-risk surgical patients.

  • Less invasive than open surgery.

✔️ Surgical AVR (Aortic Valve Replacement)

  • For younger, low-risk patients or those needing complex repairs.

  • Requires sternotomy and cardiopulmonary bypass.

Mechanical Circulatory Support (MCS)

🚨 Left Ventricular Assist Device (LVAD)

  • Used in end-stage HFrEF as bridge to transplant or destination therapy.

  • Requires lifelong anticoagulation.

🚨 Extracorporeal Membrane Oxygenation (ECMO)

  • Veno-arterial (VA-ECMO): For cardiogenic shock, cardiac arrest.

  • Veno-venous (VV-ECMO): For severe ARDS, respiratory failure.

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